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A phase IIa randomized controlled clinical and histological pilot study evaluating rhGDF‐5/β‐TCP for periodontal regeneration

Identifieur interne : 004A07 ( Main/Exploration ); précédent : 004A06; suivant : 004A08

A phase IIa randomized controlled clinical and histological pilot study evaluating rhGDF‐5/β‐TCP for periodontal regeneration

Auteurs : Andreas Stavropoulos [Danemark, Grèce] ; Peter Windisch [Hongrie] ; Istvan Gera [Hongrie] ; Björn Capsius [Allemagne] ; Anton Sculean [Suisse] ; Ulf M. E. Wikesjö [États-Unis]

Source :

Journal of Clinical Periodontology [ 0303-6979 ] ; 2011-11.

RBID : ISTEX:4D10C9ED2F62A5249C77D90E40303BE40957F60C

English descriptors

Abstract

The primary objective of this study was to clinically and histologically evaluate periodontal wound healing/regeneration following surgical implantation of recombinant human growth/differentiation factor‐5 (rhGDF‐5) adsorbed onto a particulate β‐tricalcium phosphate (β‐TCP) carrier rhGDF‐5/β‐TCP into periodontal defects in man.

Url:

https://api.istex.fr/document/4D10C9ED2F62A5249C77D90E40303BE40957F60C/fulltext/pdf

DOI: 10.1111/j.1600-051X.2011.01778.x

Affiliations:

Allemagne, Danemark, Grèce, Hongrie, Suisse, États-Unis
Attique (région), Canton de Berne, Hongrie centrale
Athènes, Berne, Budapest

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Le document en format XML

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<author><name sortKey="Windisch, Peter" sort="Windisch, Peter" uniqKey="Windisch P" first="Peter" last="Windisch">Peter Windisch</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alveolar bone</term>
<term>Apical</term>
<term>Apical extension</term>
<term>Apical extent</term>
<term>Apical termination</term>
<term>Artefactual split</term>
<term>Asterisk</term>
<term>Augmentation</term>
<term>Biopsy</term>
<term>Bone formation</term>
<term>Bone regeneration</term>
<term>Bone regeneration height</term>
<term>Bone trabeculae</term>
<term>Cellular cementum</term>
<term>Cementum</term>
<term>Cementum regeneration</term>
<term>Clinical periodontology</term>
<term>Coronal</term>
<term>Coronal extension</term>
<term>Debridement</term>
<term>Deepest aspect</term>
<term>Deepest site</term>
<term>Defect</term>
<term>Defect depth</term>
<term>Defect site</term>
<term>Defect sites</term>
<term>Evaluable</term>
<term>Evaluable biopsies</term>
<term>Foreign body reactions</term>
<term>Gingival margin</term>
<term>Growth factors</term>
<term>Histological</term>
<term>Histological evaluation</term>
<term>Histometrical</term>
<term>Histometrical evaluation</term>
<term>Implant</term>
<term>Implantation</term>
<term>Implants research</term>
<term>Intrabony</term>
<term>John wiley sons</term>
<term>Ligament</term>
<term>Neighbouring teeth</term>
<term>Periodontal</term>
<term>Periodontal defect model</term>
<term>Periodontal defects</term>
<term>Periodontal disease</term>
<term>Periodontal indications</term>
<term>Periodontal ligament regeneration</term>
<term>Periodontal regeneration</term>
<term>Periodontal repair</term>
<term>Periodontal wound</term>
<term>Periodontal wound healing</term>
<term>Periodontology</term>
<term>Pilot study</term>
<term>Pippig</term>
<term>Polimeni</term>
<term>Present study</term>
<term>Primary intention healing</term>
<term>Recombinant</term>
<term>Regenerated</term>
<term>Regenerated alveolar bone</term>
<term>Regenerated bone</term>
<term>Regeneration</term>
<term>Regenerative</term>
<term>Resident bone</term>
<term>Residual</term>
<term>Root instrumentation</term>
<term>Root planing</term>
<term>Root surface</term>
<term>Scil technology gmbh</term>
<term>Semmelweis university</term>
<term>Sinus</term>
<term>Specimen blocks</term>
<term>Stavropoulos</term>
<term>Stavropoulos wikesjo</term>
<term>Surgical</term>
<term>Surgical implantation</term>
<term>Tissue formation</term>
<term>Vertical notch</term>
<term>White asterisk</term>
<term>Wikesjo</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en"><term>Alveolar bone</term>
<term>Apical</term>
<term>Apical extension</term>
<term>Apical extent</term>
<term>Apical termination</term>
<term>Artefactual split</term>
<term>Asterisk</term>
<term>Augmentation</term>
<term>Biopsy</term>
<term>Bone formation</term>
<term>Bone regeneration</term>
<term>Bone regeneration height</term>
<term>Bone trabeculae</term>
<term>Cellular cementum</term>
<term>Cementum</term>
<term>Cementum regeneration</term>
<term>Clinical periodontology</term>
<term>Coronal</term>
<term>Coronal extension</term>
<term>Debridement</term>
<term>Deepest aspect</term>
<term>Deepest site</term>
<term>Defect</term>
<term>Defect depth</term>
<term>Defect site</term>
<term>Defect sites</term>
<term>Evaluable</term>
<term>Evaluable biopsies</term>
<term>Foreign body reactions</term>
<term>Gingival margin</term>
<term>Growth factors</term>
<term>Histological</term>
<term>Histological evaluation</term>
<term>Histometrical</term>
<term>Histometrical evaluation</term>
<term>Implant</term>
<term>Implantation</term>
<term>Implants research</term>
<term>Intrabony</term>
<term>John wiley sons</term>
<term>Ligament</term>
<term>Neighbouring teeth</term>
<term>Periodontal</term>
<term>Periodontal defect model</term>
<term>Periodontal defects</term>
<term>Periodontal disease</term>
<term>Periodontal indications</term>
<term>Periodontal ligament regeneration</term>
<term>Periodontal regeneration</term>
<term>Periodontal repair</term>
<term>Periodontal wound</term>
<term>Periodontal wound healing</term>
<term>Periodontology</term>
<term>Pilot study</term>
<term>Pippig</term>
<term>Polimeni</term>
<term>Present study</term>
<term>Primary intention healing</term>
<term>Recombinant</term>
<term>Regenerated</term>
<term>Regenerated alveolar bone</term>
<term>Regenerated bone</term>
<term>Regeneration</term>
<term>Regenerative</term>
<term>Resident bone</term>
<term>Residual</term>
<term>Root instrumentation</term>
<term>Root planing</term>
<term>Root surface</term>
<term>Scil technology gmbh</term>
<term>Semmelweis university</term>
<term>Sinus</term>
<term>Specimen blocks</term>
<term>Stavropoulos</term>
<term>Stavropoulos wikesjo</term>
<term>Surgical</term>
<term>Surgical implantation</term>
<term>Tissue formation</term>
<term>Vertical notch</term>
<term>White asterisk</term>
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<front><div type="abstract">The primary objective of this study was to clinically and histologically evaluate periodontal wound healing/regeneration following surgical implantation of recombinant human growth/differentiation factor‐5 (rhGDF‐5) adsorbed onto a particulate β‐tricalcium phosphate (β‐TCP) carrier rhGDF‐5/β‐TCP into periodontal defects in man.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Danemark</li>
<li>Grèce</li>
<li>Hongrie</li>
<li>Suisse</li>
<li>États-Unis</li>
</country>
<region><li>Attique (région)</li>
<li>Canton de Berne</li>
<li>Hongrie centrale</li>
</region>
<settlement><li>Athènes</li>
<li>Berne</li>
<li>Budapest</li>
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<name sortKey="Stavropoulos, Andreas" sort="Stavropoulos, Andreas" uniqKey="Stavropoulos A" first="Andreas" last="Stavropoulos">Andreas Stavropoulos</name>
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<country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Windisch, Peter" sort="Windisch, Peter" uniqKey="Windisch P" first="Peter" last="Windisch">Peter Windisch</name>
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<country name="Allemagne"><noRegion><name sortKey="Capsius, Bjorn" sort="Capsius, Bjorn" uniqKey="Capsius B" first="Björn" last="Capsius">Björn Capsius</name>
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<country name="Suisse"><region name="Canton de Berne"><name sortKey="Sculean, Anton" sort="Sculean, Anton" uniqKey="Sculean A" first="Anton" last="Sculean">Anton Sculean</name>
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<country name="États-Unis"><noRegion><name sortKey="Wikesjo, Ulf M E" sort="Wikesjo, Ulf M E" uniqKey="Wikesjo U" first="Ulf M. E." last="Wikesjö">Ulf M. E. Wikesjö</name>
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A phase IIa randomized controlled clinical and histological pilot study evaluating rhGDF‐5/β‐TCP for periodontal regeneration

A phase IIa randomized controlled clinical and histological pilot study evaluating rhGDF‐5/β‐TCP for periodontal regeneration

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri